Br J Cancer. 2011 Feb 1;104(3):537-41.
Alcohol consumption and risk of renal cell cancer: the NIH-AARP diet and health study.
Lew JQ, Chow WH, Hollenbeck AR, Schatzkin A, Park Y.
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Bethesda, MD, USA.
Abstract
BACKGROUND: The effect of moderate to heavy drinking (>15 g per day) on renal cell cancer (RCC) risk is unclear.
METHOD: The relationship between alcohol consumption and RCC was examined in the NIH-AARP Diet and Health Study (n=492187, 1814 cases).
RESULTS: Compared with >0 to <5 g per day of alcohol consumption, the multivariate relative risk (95% confidence intervals) for 15 to <30 and 30 g per day was, 0.75 (0.63-0.90) and 0.71 (0.59-0.85), respectively, in men and 0.67 (0.42-1.07) and 0.43 (0.22-0.84), respectively, in women.
CONCLUSION: Alcohol consumption was inversely associated with RCC in a dose-response manner. The inverse association may be extended to 30 g per day of alcohol intake.
PMID: 21245859 [PubMed - indexed for MEDLINE]